A most important point is that patients with bacterial infections would usually respond rapidly to ascorbic acid plus a basic antibiotic determined by initial clinical impressions. If cultures subsequently proved the selection of antibiotic incorrect. usually the patient was well by that time.
In the case of a 45-year-old man who had developed osteomyelitis if the 5th metacarpal of the right hand following a cat bite, a partial imputation of the hand had been recommended and surgery scheduled. Consultants agreed. The patient delayed surgery and signed himself out if the hospital. He was given intravenous ascorbate 50 grams a day for 2 weeks. The infection resolved rapidly. While this patient had destruction of the distal end of the metacarpal, there has been no recurrence of the infection (25).
This case illustrates the frequent problem of indolent infection with an organism non-responsive to the most sophisticated antibiotic treatment which then may respond rapidly to treatment with intravenous ascorbate.
Treating simultaneously with the appropriate antibiotic plus ascorbate has the additional advantage that if, unexpectedly, the infection is actually viral, the infection will be suppressed and the incidence of allergic reaction to the antibiotic reduced.