Belfield (32) has had similar results in veterinary medicine during distemper and kennelfever indogs with intravenous ascorbate. Although dogs produce their own ascorbate, they do not produce enough to neutralize the toxicity of these diseases. This effect in animals could hardly be a placebo.
It would be possible to conduct a double blind study on intravenous ascorbate; however, doses would have to be determined by someone experienced with this method.
Part of the difficulty many have with understanding ascorbate is that claims for its benefits seem too many. Most of these clinical results merely indicate that large doses of ascorbate augment the healing abilities of the body already known to be dependent upon minimal doses of ascorbate.
I anticipate that other essential nutrients will be found being utilized at unexpectedly rapid rates in disease states. Complications caused by failures in systems dependent upon those nutrients will be found. The magnitude of supplementations necessary to avert those complications will seem extraordinary by standards accepted today.